L-Glutathione

Shop Glutathione 1500mg from Spark Peptide. Independently third-party tested for batch-to-batch consistency, certified ≥99% purity with lot-specific COAs. Free USPS Priority shipping on orders over $200. Sold for research use only.

Glutathione Characteristics

Note: Glutathione exists in two forms—reduced (GSH) and oxidized (GSSG). This product contains the reduced form. The tripeptide is sensitive to oxidation upon reconstitution, particularly in neutral or alkaline solutions, so researchers should prepare fresh working solutions or add stabilizers for extended use.

Glutathione - Handling & Storage Guidelines

Proper handling and storage are important for preserving glutathione in its reduced form, minimizing oxidation, and supporting the integrity and reproducibility of laboratory research.

• Storage of Lyophilized Powder: Store unopened lyophilized glutathione in a tightly sealed vial at -20°C, protected from light and moisture. Maintaining dry, frozen storage conditions helps preserve sample stability prior to use.
• Preparation of Working Solutions: When preparing a working solution, use an appropriate sterile reconstitution solution or compatible laboratory buffer in accordance with validated laboratory procedures. Because glutathione is susceptible to oxidation once in solution, laboratories commonly prepare working solutions immediately before use whenever practical.
• Oxidation Considerations: Reduced glutathione readily oxidizes when exposed to oxygen, moisture, heat, and certain trace metal ions. Oxidation may also occur more rapidly under less favorable pH conditions. Laboratory handling practices should therefore be designed to minimize environmental exposure and help preserve sample integrity throughout the course of an experiment.
• Storage of Prepared Solutions: Store prepared solutions under refrigerated or frozen conditions as appropriate for the research protocol. Where suitable, laboratories commonly prepare aliquots to reduce repeated freeze-thaw cycles and maintain sample quality during storage.
• Laboratory Safety: Glutathione is intended exclusively for laboratory research. Handle all materials in accordance with institutional biosafety, laboratory safety, and chemical handling procedures, and dispose of waste in accordance with applicable institutional and regulatory requirements.

Glutathione - COA / Quality Assurance

Spark Peptide provides comprehensive Certificates of Analysis (COAs) for every glutathione batch for transparency and traceability. A COA delivers detailed analytical data essential for experimental reproducibility, regulatory compliance, and quality assurance documentation.

That includes information on:

• Peptide Identity Verification: Confirmed through high-performance liquid chromatography (HPLC) retention time matching and mass spectrometry analysis, verifying the correct molecular weight of 307.32 g/mol and tripeptide structure.
• Purity Assessment: Quantified via HPLC with detection methods measuring both reduced glutathione (GSH) content and potential oxidized glutathione (GSSG) or other impurities, typically demonstrating ≥98% purity for research-grade material.
• Sterility Testing: Conducted according to USP <71> sterility testing protocols to ensure freedom from bacterial and fungal contamination.
• Endotoxin Levels: Measured via Limulus Amebocyte Lysate (LAL) assay to ensure compliance with research-grade standards, typically <1.0 EU/mg.
• Storage Recommendations: Tailored guidance for optimal stability based on the specific tested lot, including temperature requirements and expiration dating.

Spark Peptide partners with leading independent analytical laboratories, including Janoshik and Finnrick Analytics, to conduct rigorous testing free from conflicts of interest. This third-party approach ensures objective, reliable results meeting international analytical standards.

For accessibility, COAs are lot-specific, uniquely identified by batch numbers printed on product vials, and readily accessible through the Lab Tests page on our website.

Legal / Regulatory Disclaimer — Glutathione

Synthetic glutathione is strictly for laboratory research purposes only and is not approved by the FDA or any regulatory authority for human consumption, veterinary use, clinical administration, therapeutic applications, or diagnostic procedures. This product is intended exclusively for qualified researchers operating within approved protocols and appropriate biosafety frameworks. Purchasers are solely responsible for ensuring compliance with all applicable federal, state, and local regulations governing research compounds, as well as institutional policies. Spark Peptide does not condone, support, or provide guidance for any non-research applications of this compound.